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Table 42.

Laboratory Diagnosis of Human Bite Wound Infections

There is no utility in collecting a specimen at the time of the bite; collect samples only if infection occurs.

View Large
Table 42.

Laboratory Diagnosis of Human Bite Wound Infections

There is no utility in collecting a specimen at the time of the bite; collect samples only if infection occurs.

View Large

As with human bite wounds, the oral cavity of animals is the primary source of potential pathogens and thus the anticipated etiological agent(s) is highly dependent upon the type of animal that inflicted the bite ( Table 43 ). As dogs and cats account for the majority of animal-inflicted bite wounds, the 2 most prominent groups of microorganisms initially considered in the evaluation of patients are Pasteurella spp, namely P. canis (dogs) and P. multocida subsp multocida and subsp septica (cats) or Capnocytophaga canimorsus . Other common aerobes include streptococci, staphylococci, Moraxella spp, and saprophytic Neisseria spp. Animal bite wounds are often polymicrobial in nature and include a variety of anaerobes. Due to the complexity of the microbial flora in animals, examination of cultures for organisms other than those listed in Table 43 is of little benefit since these organisms are not included in most of the commercial identification systems (conventional and automated) databases [ 229–238 ]. Matrix-assisted laser desorption–ionization mass spectrometry has proven valuable in identifying organisms when conventional phenotypic systems have failed. If rabies or herpes B infection is suspected, contact the local or state public health laboratory for assistance and advice on how to proceed.

Table 43.

Laboratory Diagnosis of Animal Bite Wound Infections

Abbreviation: RT, room temperature.

Additional potential pathogens to consider: , , spp, spp, spp, spp, spp, , , Centers for Disease Control and Prevention (CDC) group EF-4, CDC NO-1, spp, rabies, herpes B, or other viruses (refer to Section XIV).

Anaerobic transport media preserve all other organisms for culture.

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Table 43.

Laboratory Diagnosis of Animal Bite Wound Infections

Abbreviation: RT, room temperature.

Additional potential pathogens to consider: , , spp, spp, spp, spp, spp, , , Centers for Disease Control and Prevention (CDC) group EF-4, CDC NO-1, spp, rabies, herpes B, or other viruses (refer to Section XIV).

Anaerobic transport media preserve all other organisms for culture.

View Large

Infections from trauma are usually caused by exogenous or environmental microbial flora but can be due to the individual’s endogenous (normal) flora ( Table 44 ). It is strongly recommended that specimens not be submitted for culture within the first 48 hours posttrauma as growth from specimens collected within this time frame most likely represents environmental flora acquired at the time of the trauma episode (motor vehicle accident, stabbings, gunshot wounds, etc). The optimal time to acquire cultures is immediately after debridement of the trauma site [ 239–242 ]. It is strongly recommended that initial cultures focus on common pathogens, with additional testing being reserved for uncommon or rare infections associated with special circumstances (eg, detection of Vibrio spp following saltwater exposure) or patients with chronic manifestations of infection or who do not respond to an initial course of therapy.

Solving Forward-Backward Stochastic Differential Equations Explicitly – a Four Step Scheme (1994)

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by Jiongmin Yong

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@ARTICLE{Yong94solvingforward-backward,author = {Jiongmin Yong},title = {Solving Forward-Backward Stochastic Differential Equations Explicitly – a Four Step Scheme},journal = {Prob. Th. Rel. Fields},year = {1994},pages = {339--359}}

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Abstract

Abstract. The problem of nding adapted solutions to systems of coupled linear forwardbackward stochastic di erential equations (FBSDEs, for short) is investigated. A necessary condition of solvability leads to a reduction of general linear FBSDEs to a special one. By some ideas from controllability in control theory, using some functional analysis, we obtain a necessary and su cient condition for the solvability of the linear FBSDEs with the processes Z (serves as a correction, see x1) being absent in the drift. Then a Riccati type equation for matrix-valued (not necessarily square) functions is derived using the idea of the Four-Step-Scheme (introduced in [11] for general FBSDEs). The solvability of such a Riccati type equation is studied which leads to a representation of adapted solutions to linear FBSDEs. Keywords. Linear forward-backward stochastic di erential equations, adapted solution, Riccati type equation. AMS Mathematics subject classi cation. 60H10.

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